{"id":8755,"date":"2015-05-28T15:17:55","date_gmt":"2015-05-28T15:17:55","guid":{"rendered":"https:\/\/dev.93-93-113-41.plesk.page\/?page_id=8755"},"modified":"2024-06-01T12:24:40","modified_gmt":"2024-06-01T10:24:40","slug":"colangitis-esclerosante-primaria","status":"publish","type":"page","link":"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/","title":{"rendered":"Colangitis Esclerosant Prim\u00e0ria"},"content":{"rendered":"

Qu\u00e8 \u00e9s la Colangitis Esclerosant Prim\u00e0ria?<\/h2>\n

La Colangitis Esclerosant Prim\u00e0ria (CEP) \u00e9s una malaltia cr\u00f2nica que afecta les vies biliars a causa d’un atac de les pr\u00f2pies defenses del nostre organisme (autoimmunitat) cap a les c\u00e8l\u00b7lules normals de les vies biliars, el que produeix inflamaci\u00f3 i cicatrius (fibrosi) el que pot comportar a estretors i alteraci\u00f3 del par\u00e8nquima hep\u00e0tic.<\/p>\n

Hi ha una important associaci\u00f3 amb la Malaltia Inflamat\u00f2ria Intestinal (MII), especialment amb la Colitis ulcerosa (entre un 75-90% dels pacients amb CEP tenen MII).<\/p>\n

Quins s\u00edmptomes t\u00e9?<\/h2>\n

La malaltia pot cursar amb brots de picor intensa en tot el cos, cansament i coloraci\u00f3 groguenca de la pell. En alguns casos pot haver fins i tot febre al obstruir-alguna de les vies biliars (colangitis). Per l’associaci\u00f3 amb la MII, els pacients poden presentar s\u00edmptomes propis d’aquesta malaltia (sagnat rectal, diarrea, etc.). A m\u00e9s, aquests pacients presenten un augment en la incid\u00e8ncia de c\u00e0ncer de c\u00f2lon que en la poblaci\u00f3 general.<\/p>\n

Com es diagnostica?<\/h2>\n

El diagn\u00f2stic es realitza amb anal\u00edtiques i proves d’imatge.
\nEn l’anal\u00edtica \u00e9s t\u00edpic trobar elevaci\u00f3 de fosfatasa alcalina, gamma-GT i gamma-globulina i alguns tipus d’anticossos (ANCA, anticardiolipina o ANA).
\nA la Colangiografia per resson\u00e0ncia magn\u00e8tica i la Colangiopancreatografia retr\u00f2grada endosc\u00f2pica es poden objectivar les estretors de les vies biliars ocasionades per la inflamaci\u00f3.
\nLa fibrosi es pot mesurar a trav\u00e9s de t\u00e8cniques de elastograf\u00eda de transici\u00f3 hep\u00e0tica (FibroScan CAP\u00ae<\/a>).
\nLa bi\u00f2psia hep\u00e0tica resulta poc rendible en molts casos perqu\u00e8 \u00e9s dif\u00edcil seleccionar una zona afectada, per\u00f2 \u00e9s molt espec\u00edfica.<\/p>\n

Quin pron\u00f2stic t\u00e9?<\/h2>\n

La CEP \u00e9s una malaltia que cursa amb brots d’inflamaci\u00f3. Segons el severa que sigui aquesta inflamaci\u00f3 es poden produir casos d’infecci\u00f3 en les zones de estretor (colangitis bacteriana) de forma aguda. Amb el pas del temps, aquestes estretors es fan fibr\u00f3ticas podent afavorir l’aparici\u00f3 d’un tumor de les vies biliars (colangiocarcinoma).
\nEl pron\u00f2stic ve marcat per la severitat d’aquestes complicacions aix\u00ed com de l’evoluci\u00f3 de la malaltia inflamat\u00f2ria intestinal o el c\u00e0ncer colorectal en cas de presentar-lo.<\/p>\n

Quin tractament t\u00e9?<\/h2>\n

El tractament amb \u00c0cid ursodesoxic\u00f3lico ha demostrat, amb baixa evid\u00e8ncia, frenar la malaltia.
\nEn ocasions la dieta amb oli MCT a for\u00e7a de triglic\u00e8rids de cadena mitjana, pot resultar beneficiosa.
\nQuan apareix una complicaci\u00f3 aguda s’ha de tractar de forma espec\u00edfica.
\nEl trasplantament hep\u00e0tic s’ha de valorar sempre que s’observin signes de malaltia hep\u00e0tica avan\u00e7ada o infeccions de repetici\u00f3.<\/p>\n","protected":false},"excerpt":{"rendered":"

Qu\u00e8 \u00e9s la Colangitis Esclerosant Prim\u00e0ria? La Colangitis Esclerosant Prim\u00e0ria (CEP) \u00e9s una malaltia cr\u00f2nica que afecta les vies biliars a causa d’un atac de les pr\u00f2pies defenses del nostre organisme (autoimmunitat) cap a les […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":0,"parent":7391,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8755","page","type-page","status-publish"],"yoast_head":"\nColangitis Esclerosant Prim\u00e0ria - Servidigest<\/title>\n<meta name=\"description\" content=\"Colangitis Esclerosant Prim\u00e0ria\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Colangitis Esclerosant Prim\u00e0ria - Servidigest\" \/>\n<meta property=\"og:description\" content=\"Colangitis Esclerosant Prim\u00e0ria\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/\" \/>\n<meta property=\"og:site_name\" content=\"Servidigest\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/servidigest\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-01T10:24:40+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@servidigest\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/\",\"url\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/\",\"name\":\"Colangitis Esclerosant Prim\u00e0ria - Servidigest\",\"isPartOf\":{\"@id\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/#website\"},\"datePublished\":\"2015-05-28T15:17:55+00:00\",\"dateModified\":\"2024-06-01T10:24:40+00:00\",\"description\":\"Colangitis Esclerosant Prim\u00e0ria\",\"breadcrumb\":{\"@id\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/#breadcrumb\"},\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/serveis\/aparell-digestiu\/hepatologia\/colangitis-esclerosante-primaria\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Serveis M\u00e8dics de Cl\u00ednica ServiDigest\",\"item\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/servicios\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Aparell digestiu\",\"item\":\"https:\/\/dev.93-93-113-41.plesk.page\/ca\/servicios\/aparato-digestivo\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Hepatologia. 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